From opulent luxury hotels to kitschy boutique hotels, you can book your hotel room in Mayaguez at the lowest rate guaranteed on Agoda.com. Guests find many of the 3 hotels in Mayaguez an attraction in themselves. Many areas, each with a distinctive atmosphere, are just waiting to be discovered across the city. The city is served by 1 airports which means it is accessible from almost every major city in the world. There are so many things to do, you may want to stay an extra week or so to experience them all. Book your next trip to Mayaguez with Agoda, backed by our low price guarantee.