Planning a trip to Central America and Caribbean? Perhaps you'd like to visit some of the continent's most popular travel destinations, like Panama. Why pay more if you don't have to? Agoda.com offers the best selection of hotels in Panama to fit your travel budget and preferences. Consisting of 13 regions, each with its own unique appeal, the country offers visitors plenty of different areas to explore. Oh and whatever you do, Panama City, Bocas del Toro, Tocumen are great cities to visit. Choose your travel dates and let Agoda.com find the perfect hotel in Panama for you. Our Lowest Rate Guarantee means you won’t find better rates anywhere.