If you are looking for a holiday destination in Central America and Caribbean, then Panama is the place to go, offering something for everyone. Agoda.com offers the best prices for hotels in Panama, with 407 hotels ready for instant reservation via our secure online booking engine. With 13 different regions, the country offers its visitors a great diversity of beautiful landscapes as well as a vibrant culture and lifestyle. The country offers 48 unique cities to discover such as Panama City, Bocas del Toro, Boquete. With our best price guarantee, we are determined to offer you the best hotels at the best prices.