Agoda.com offers a selection of the very best hotels in Santo Antonio, Sao Tome and Principe to ensure your visit fits your expectations. With over 8 different establishments, there is a great variety to choose from. Many areas, each with a distinctive atmosphere, are just waiting to be discovered across the city. Santo Antonio has many attractions to explore with its fascinating past, intriguing present and exciting future. There are so many things to do, you may want to stay an extra week or so to experience them all. Agoda.com offers professional reviews and ratings of hotels in Santo Antonio so you can enjoy the perfect stay.